ESR 1

Integrated liquid biopsy for cancer diagnostics via genomic markers detection
Host institution/company
University of Parma (Italy)
Supervisors
Academic
Prof. Annamaria Cucinotta, Group of Applied Electromagnetics (GAEM), Department of Engineering and Architecture, University of Parma; 
Prof. Stefano Selleri, Group of Applied Electromagnetics (GAEM), Department of Engineering and Architecture, University of Parma;
Prof. Daniel Milanese, Group of Materials Engineering, Department of Engineering and Architecture, University of Parma.

Industrial
Dr. Catalina David, Jobin Yvon SAS.

Type of contract
36-months full-time research grant within the PHAST-ETN project
Brief description of the project
The GAEM group has been working on optical sensors for several years for various applications. The proposed activity deals with the development of novel sensors able to detect ex-vivo tumor markers using Raman spectroscopy.
Body fluids will be put into contact with two different platforms: optofluidic chips and optical fibre probes. Different functionalization process will be explored, including gold nanopillars and mi-RNA and PNA customized receptors.

The ESR will work in collaboration with Horiba France SAS and will be seconded at Politecnico di Torino (Italy), Friedrich Schiller University (Germany), Tyndall Institute (Ireland), and Horiba Jobin Yvon SAS (France).
Qualifications
Essential 
Applicants should hold or expect to attain, as a minimum an MSc in Electronic/Biomedical/Management/Mechanical/Material Engineering with a background in Optics and Photonics, Chemistry, Physics or related areas.
Knowledge and Experience
Essential 
A demonstrated knowledge of at least two of the following: photonics, electromagnetic fields, optical sensing, biosensing.

Desirable
Research project carried out in at least one of the above disciplines. Knowledge of basic principles in optical sensors and biosensors and guided-wave photonic biosensors and sensing mechanisms.
Skills and Competencies
Essential 
- Applicants whose first language is not English must submit evidence of competency in English.
- Evidence of interest, aptitude and research experience in the above disciplines.
Further information
For any informal queries, please contact Prof. Annamaria Cucinotta by email at annamaria.cucinotta@unipr.it or stefano.selleri@unipr.it.
Information sheet

Other ESR Positions

ESR 2
Point-of-care Raman microspectroscopy for detecting tumour markers in body liquids
ESR 3
Spectral tissue imaging for ex-vivo cancer diagnosis and survey
ESR 4
Integrated optical fibre sensors for intravital monitoring
ESR 5
Hybrid diffuse optical monitoring and theranostics with blood flow and oxygen metabolism biomarkers on pre-clinical models
ESR 6
Time-gated diffuse optical spectroscopy for deep tissue diagnostics
ESR 7
Multimodal nonlinear imaging for clinical diagnosis in combination with laser tissue ablation for selective tissue removal
ESR 8
Micro-optical imaging system for multimodal non-linear endospectroscopy
ESR 9
Multimodal endo-microscopy for improved in-vivo colorectal cancer diagnosis
ESR 10
Multimodal intraoperative handheld forward-imaging probe
ESR 11
Towards multifunctional multimaterial optical fibres for diagnostic and treatment
ESR 12
Development of advanced online dosimetry algorithms for photodynamic therapy of tumours
ESR 13
Diffuse optical monitoring and prediction of neoadjuvant chemotherapy for personalized breast cancer management
ESR 14
Tissue identification for surgical guidance using biophotonics
ESR 15
Micro-camera for hyperspectral imaging for in-vivo probing

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